Hello shopfres, welcome to ask medical doctor .com. The most likely possible causes have been very well
explained by Dr.J.S.Anand. I would like to add on some other possibilities which have to be ruled out in your
case. Knee swelling, pinkish in colour, mostly should be associated with local rise in temperature {warm, when
compared to other knee} suggest inflammation secondary to Rheumatoid Arthritis. The other characteristic
feature associated in your case is big toe pain accompanied with numbness. The other possible causes are
Kneecap Bursitis, Gout, Pseudo gout, Cysts, Tumors or may be over use. The important diagnostic test is
Arthrocentesis. This procedure involves withdrawal of fluid from the knee and sending it for analysis like
cell type, cell count, uric acid levels and cultures for bacteria. Other laboratory investigations include C
reactive protein, ESR, complete blood picture and serum electrolytes. Treatment involves NSAIDS {non steroidal
anti inflammatory drugs}, treat the underlying cause, rest and ice compression. Apart from this Diabetic
Neuropathy has to be ruled out as suggested by Dr. Anand. Get a FBS, PLBS and HbA1c done. Hope this additional
information helps you. Any further doubts kindly keep posting. Regards